Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 9/20 | 0.40 |
| ▸ | CES2 | O00748 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293730 | 0.74 | CES1 (0.42) | CES1CES2ALDH1A1MAPK1KMT2A | |
| SCHEMBL28168721 | 0.74 | CES1 (0.45) | CES1CES2ALDH1A1MAPK1HIF1A | |
| SCHEMBL9548329 | 0.74 | SMN1; SMN2 (0.44) | CES1CES2ALDH1A1HIF1A | |
| SCHEMBL28765023 | 0.73 | CES1 (0.41) | CES1CES2ALDH1A1KMT2AGAA | |
| SCHEMBL11268210 | 0.72 | ALDH1A1 (0.38) | CES1CES2ALDH1A1TRPA1MAPK1 | |
| SCHEMBL10516214 | 0.71 | CES1 (0.43) | CES1CES2ALDH1A1KMT2AGAA | |
| SCHEMBL31272718 | 0.71 | CES1 (0.47) | CES1CES2ALDH1A1MAPK1KMT2A | |
| SCHEMBL10956940 | 0.71 | CES1 (0.47) | CES1CES2ALDH1A1MAPK1KMT2A | |
| SCHEMBL4364092 | 0.70 | CES1 (0.50) | CES1CES2ALDH1A1KMT2AMAPT | |
| SCHEMBL28866511 | 0.70 | CES1 (0.44) | CES1CES2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322431-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |