Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.57 |
| ▸ | TNKS | O95271 | 1/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.57 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.57 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208890 | 0.97 | AKR1C3 (0.64) | AKR1C3HDAC8MAPTTDP1PARP10 | |
| SCHEMBL9242893 | 0.95 | MAPT (0.60) | AKR1C3HDAC8MAPTTDP1PARP10 | |
| SCHEMBL11208893 | 0.94 | AKR1C3 (0.70) | AKR1C3HDAC8MAPTTDP1PARP10 | |
| SCHEMBL28051885 | 0.92 | AKR1C3 (0.67) | AKR1C3HDAC8MAPTTDP1PARP10 | |
| SCHEMBL11149811 | 0.89 | PARP10 (0.67) | AKR1C3MAPTTDP1PARP10KMT2A | |
| SCHEMBL69684 | 0.87 | NSD2 (0.63) | AKR1C3MAPTTDP1PARP10KMT2A | |
| SCHEMBL9809043 | 0.87 | PARP10 (0.69) | MAPTTDP1PARP10KMT2AMEN1 | |
| SCHEMBL9809037 | 0.87 | PARP10 (0.69) | MAPTTDP1PARP10KMT2AMEN1 | |
| SCHEMBL6938778 | 0.85 | AKR1C3 (0.72) | AKR1C3HDAC8MAPTPARP10TNKS | |
| SCHEMBL70401 | 0.85 | PARP10 (0.67) | MAPTTDP1PARP10ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57117528-A | — | — | None | — | — | JP | disclosed |
| JP-S57117528-A | WHOLLY AROMATIC POLYETHER ESTER | TORAY IND INC | 1982-07-22 | — | — | JP | disclosed |