Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.58 |
| ▸ | FEN1 | P39748 | 1/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938784 | 0.98 | AKR1C3 (0.70) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL27516805 | 0.90 | AKR1C3 (0.64) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL9304626 | 0.89 | AKR1C3 (0.61) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL9187797 | 0.85 | AKR1C3 (0.58) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL11215809 | 0.85 | AKR1C3 (0.68) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL521860 | 0.85 | AKR1C3 (0.68) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL8897485 | 0.84 | AKR1C3 (0.78) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL30445868 | 0.84 | AKR1C3 (1.00) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL21887184 | 0.84 | AKR1C3 (0.78) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL28620841 | 0.84 | PARP10 (0.62) | AKR1C3ERCC5FEN1TNKSPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |