SCHEMBL11208893

SCHEMBL11208893

O=C(O)c1ccc(Oc2cccc(C(=O)Oc3ccccc3)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.70
SRD5A2 P31213 3/20 0.60
PARP10 Q53GL7 2/20 0.55
TNKS O95271 1/20 0.55
PARP15 Q460N3 1/20 0.55
PARP14 Q460N5 1/20 0.55
TNKS2 Q9H2K2 1/20 0.55
PARP2 Q9UGN5 1/20 0.55
KMO O15229 1/20 0.55
KDM4E B2RXH2 1/20 0.55
HDAC8 Q9BY41 1/20 0.54
MAPT P10636 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
NR1H4 Q96RI1 1/20 0.54
POLB P06746 2/20 0.51
NPC1 O15118 1/20 0.51
CYP2C9 P11712 1/20 0.51
RAB9A P51151 1/20 0.51
ALDH1A1 P00352 2/20 0.50
ERCC5 P28715 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28051885 0.98 AKR1C3 (0.67) AKR1C3SRD5A2PARP10TNKSPARP15
SCHEMBL11208890 0.94 AKR1C3 (0.64) AKR1C3SRD5A2PARP10TNKSPARP15
SCHEMBL11215809 0.94 AKR1C3 (0.68) AKR1C3PARP10TNKSPARP15PARP14
SCHEMBL9242893 0.89 MAPT (0.60) AKR1C3SRD5A2PARP10TNKSPARP15
Terephthalic Acid SCHEMBL10678592 0.89 MAPT (0.57) AKR1C3SRD5A2PARP10KDM4EMAPT
Terephthalic Acid SCHEMBL6660728 0.87 AKR1C3 (0.58) AKR1C3SRD5A2PARP10KDM4EMAPT
SCHEMBL11273083 0.87 PARP10 (0.58) PARP10KDM4EMAPTTDP1NPC1
SCHEMBL70012 0.87 AKR1C3 (0.85) AKR1C3SRD5A2PARP10TNKSPARP15
SCHEMBL30307447 0.87 AKR1C3 (0.85) AKR1C3SRD5A2PARP10TNKSPARP15
SCHEMBL16429240 0.87 AKR1C3 (0.85) AKR1C3SRD5A2PARP10TNKSPARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58219225-A None JP disclosed
JP-S58219225-A WHOLLY AROMATIC POLYETHER ESTER HAVING HIGH ELASTICITY AGENCY OF IND SCIENCE & TECHNOL 1983-12-20 JP disclosed