SCHEMBL11215973

SCHEMBL11215973

Cc1ccc2c(c1)C(=O)c1cc(Cl)ccc1C2=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.67
MAOA P21397 1/20 0.63
MAOB P27338 1/20 0.63
S100A4 P26447 2/20 0.61
HSP90AA1 P07900 1/20 0.52
LCK P06239 1/20 0.50
ALKBH3 Q96Q83 1/20 0.49
AGTR1 P30556 1/20 0.47
CES1 P23141 2/20 0.46
TGM2 P21980 1/20 0.46
PPOX P50336 1/20 0.45
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
NQO1 P15559 2/20 0.42
POR P16435 2/20 0.42
BCL2 P10415 1/20 0.42
MCL1 Q07820 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11215991 1.00 ELANE (0.67) ELANEMAOAMAOBS100A4HSP90AA1
Tectoquinone SCHEMBL11591324 0.94 ELANE (0.78) ELANEMAOAMAOBS100A4HSP90AA1
SCHEMBL2144503 0.93 ELANE (0.75) ELANEMAOAMAOBS100A4HSP90AA1
SCHEMBL4229683 0.87 S100A4 (0.80) ELANEMAOAMAOBS100A4HSP90AA1
SCHEMBL182959 0.87 ELANE (0.86) ELANEMAOAMAOBLCKALKBH3
SCHEMBL353693 0.87 S100A4 (0.80) ELANEMAOAMAOBS100A4HSP90AA1
SCHEMBL583153 0.87 ELANE (0.86) ELANEMAOAMAOBLCKALKBH3
SCHEMBL27717180 0.85 S100A4 (0.64) ELANEMAOAMAOBS100A4HSP90AA1
SCHEMBL23271900 0.83 S100A4 (0.67) ELANEMAOAMAOBS100A4HSP90AA1
SCHEMBL30002985 0.83 MAOA (0.68) ELANEMAOAMAOBS100A4LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4355012-A Mixed anthraquinonedisulfonic acids AMERICAN COLOR & CHEMICAL CORPORATION (US) 1982-10-19 US disclosed