SCHEMBL30002985

SCHEMBL30002985

Cc1ccc2c(c1)C(=O)C(Cl)=C(Cl)C2=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.68
MAOB P27338 1/20 0.68
ELANE P08246 1/20 0.65
IDO1 P14902 1/20 0.52
DNMT1 P26358 1/20 0.52
DNMT3L Q9UJW3 1/20 0.52
DNMT3A Q9Y6K1 1/20 0.52
ALKBH3 Q96Q83 2/20 0.51
LCK P06239 1/20 0.49
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
MITF O75030 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA7 P43166 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9643596 1.00 MAOA (0.68) MAOAMAOBELANEIDO1DNMT1
SCHEMBL9628207 0.90 MAOA (0.73) MAOAMAOBELANEIDO1DNMT1
SCHEMBL7812020 0.86 TDP2 (0.60) MAOAMAOBELANEIDO1DNMT1
SCHEMBL7812173 0.86 TDP2 (0.60) MAOAMAOBELANEIDO1DNMT1
SCHEMBL30003080 0.86 TDP2 (0.60) MAOAMAOBELANEIDO1DNMT1
SCHEMBL182959 0.85 ELANE (0.86) MAOAMAOBELANEALKBH3LCK
SCHEMBL583153 0.85 ELANE (0.86) MAOAMAOBELANEALKBH3LCK
SCHEMBL11215973 0.83 ELANE (0.67) MAOAMAOBELANEALKBH3LCK
SCHEMBL11215991 0.83 ELANE (0.67) MAOAMAOBELANEALKBH3LCK
SCHEMBL22799422 0.81 ELANE (0.78) MAOAMAOBELANEALKBH3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed