Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724448 | 0.84 | ADRA2C (0.47) | ADRA2CGSK3BTDP1HPGDALDH1A1 | |
| SCHEMBL4054017 | 0.82 | HPGD (0.54) | ADRA2CHPGDALDH1A1CES1CES2 | |
| SCHEMBL1545820 | 0.81 | HPGD (0.49) | ADRA2CHPGDALDH1A1CES1CES2 | |
| SCHEMBL3657378 | 0.79 | ADRA2C (0.46) | ADRA2CGSK3BTDP1HPGDALDH1A1 | |
| SCHEMBL4433083 | 0.79 | CES2 (0.50) | ADRA2CHPGDALDH1A1CES1CES2 | |
| SCHEMBL28199079 | 0.79 | CES2 (0.50) | ADRA2CHPGDALDH1A1CES1CES2 | |
| SCHEMBL19248951 | 0.79 | HDAC3 (0.56) | ADRA2CTDP1L3MBTL1MAPTLMNA | |
| SCHEMBL11218379 | 0.79 | HDAC3 (0.56) | ADRA2CTDP1L3MBTL1MAPTLMNA | |
| SCHEMBL28986867 | 0.78 | ALDH1A1 (0.50) | ADRA2CGSK3BTDP1HPGDALDH1A1 | |
| SCHEMBL3467347 | 0.78 | NR4A2 (0.48) | ADRA2CGSK3BTDP1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309422-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |