Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216143 | 0.75 | KDM4E (0.32) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL7846851 | 0.73 | HRH3 (0.38) | HRH3 | |
| SCHEMBL9782473 | 0.65 | ESR2 (0.35) | ESR1ESR2NR3C1PGR | |
| SCHEMBL2967628 | 0.63 | OPRM1 (0.34) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL29288705 | 0.63 | MAOB (0.36) | KDM4E | |
| SCHEMBL3310654 | 0.62 | MGAM (0.47) | KDM4EALDH1A1CYP3A4MAPTHSD17B10 | |
| SCHEMBL30146748 | 0.62 | MAOA (0.39) | — | |
| SCHEMBL8370012 | 0.62 | MGAM (0.47) | KDM4EALDH1A1CYP3A4MAPTHSD17B10 | |
| SCHEMBL7557445 | 0.62 | MAOA (0.39) | — | |
| SCHEMBL30623127 | 0.62 | SCD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021827-B1 | POLYALKYLHYDROXYCHROMENE AND PROCESS FOR PREPARING THE SAME | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1983-05-11 | — | — | EP | disclosed |
| US-4323505-A | HERBICIDES, FUNGICIDES | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0021827-A1 | Polyalkylhydroxychromene and process for preparing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-07 | — | — | EP | disclosed |