SCHEMBL11216232

SCHEMBL11216232

O=C1OCCN1c1ccc(Cl)c(Cl)c1O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 10/20 0.36
NOTUM Q6P988 3/20 0.35
F10 P00742 1/20 0.32
NAAA Q02083 2/20 0.32
FPR1 P21462 1/20 0.32
FPR2 P25090 1/20 0.32
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11216231 0.79 CYP3A4 (0.34) CMA1F10NAAAFPR1FPR2
SCHEMBL11221987 0.75 CYP3A4 (0.37) CMA1F10NAAAGPR55
SCHEMBL11223731 0.74 HSP90AA1 (0.39) CMA1NAAAHPGDTSHRHSD17B10
SCHEMBL11486385 0.73 MAPT (0.57) CMA1HPGDTSHRCASP1HSD17B10
SCHEMBL12362777 0.72 TNKS (0.40) CMA1F10TSHRHSD17B10
SCHEMBL29182832 0.72 MAPT (0.39) CMA1HPGD
SCHEMBL14899249 0.70 GAA (0.42) NOTUMNAAA
SCHEMBL23466566 0.70 KMT2A (0.53) NAAAFPR1FPR2TSHR
SCHEMBL29758149 0.70 KMT2A (0.53) NAAAFPR1FPR2TSHR
SCHEMBL29758148 0.70 KMT2A (0.53) NAAAFPR1FPR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023257-B1 Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1982-06-30 EP claimed
EP-0023257-A1 Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1981-02-04 EP claimed
EP-0023257-A1 Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1981-02-04 EP disclosed