Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 6/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221987 | 0.79 | CYP3A4 (0.37) | CYP3A4MAPK1CMA1NAAAF10 | |
| SCHEMBL11216232 | 0.79 | CMA1 (0.36) | CMA1NAAAF10FPR1FPR2 | |
| SCHEMBL11223731 | 0.75 | HSP90AA1 (0.39) | CMA1NAAA | |
| SCHEMBL14899249 | 0.75 | GAA (0.42) | NAAAHTTKMT2A | |
| SCHEMBL22854543 | 0.73 | NAAA (0.37) | NAAAHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL12362782 | 0.73 | F10 (0.39) | CMA1NAAAF10 | |
| SCHEMBL28686162 | 0.73 | CMA1 (0.46) | CMA1 | |
| SCHEMBL23466566 | 0.71 | KMT2A (0.53) | CYP3A4NAAAHTTLMNAKMT2A | |
| SCHEMBL29758148 | 0.71 | KMT2A (0.53) | CYP3A4NAAAHTTLMNAKMT2A | |
| SCHEMBL29758149 | 0.71 | KMT2A (0.53) | CYP3A4NAAAHTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023257-B1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-06-30 | — | — | EP | claimed |
| EP-0023257-A1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-02-04 | — | — | EP | claimed |
| EP-0023257-A1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-02-04 | — | — | EP | disclosed |