Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557633 | 0.80 | KEAP1 (0.44) | GAAKDM4ENOTUMNAAAFAAH | |
| SCHEMBL138181 | 0.80 | KEAP1 (0.44) | GAAKDM4ENOTUMNAAAFAAH | |
| SCHEMBL3361698 | 0.79 | MGLL (0.43) | KDM4ENOTUMNAAAFAAHTNKS | |
| SCHEMBL8502875 | 0.79 | MGLL (0.43) | KDM4ENOTUMNAAAFAAHTNKS | |
| SCHEMBL4543332 | 0.79 | DDB1 (0.50) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL2750210 | 0.79 | MEN1 (0.56) | KDM4EPOLBL3MBTL1KMT2AMEN1 | |
| SCHEMBL31518544 | 0.78 | L3MBTL1 (0.49) | GAAPOLBNOTUMNAAAFAAH | |
| SCHEMBL7823337 | 0.77 | KEAP1 (0.42) | GAAKDM4EL3MBTL1TNKSKMT2A | |
| SCHEMBL19127710 | 0.77 | KMT2A (0.40) | KDM4ENOTUMNAAAFAAHTNKS | |
| SCHEMBL7814732 | 0.77 | KEAP1 (0.46) | GAAPOLBL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431607-B2 | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2013-04-30 | — | — | US | disclosed |