Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 8/20 | 0.34 |
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216231 | 0.79 | CYP3A4 (0.34) | CYP3A4MAPK1CMA1NAAAF10 | |
| SCHEMBL12362777 | 0.75 | TNKS (0.40) | CYP3A4CMA1KDM1AMAOAMAOB | |
| SCHEMBL11216232 | 0.75 | CMA1 (0.36) | CMA1NAAAF10GPR55 | |
| SCHEMBL12362782 | 0.75 | F10 (0.39) | CMA1NAAAKDM1AMAOAMAOB | |
| SCHEMBL11223731 | 0.71 | HSP90AA1 (0.39) | CMA1NAAA | |
| SCHEMBL16703518 | 0.70 | MAPT (0.38) | CYP3A4CMA1NAAAKDM1AMAOA | |
| SCHEMBL21723494 | 0.69 | SLC6A2 (0.48) | CMA1 | |
| SCHEMBL14899249 | 0.67 | GAA (0.42) | NAAA | |
| SCHEMBL10364106 | 0.67 | ACHE (0.36) | CMA1F10 | |
| SCHEMBL13167913 | 0.66 | HSD11B1 (0.47) | CMA1NAAAKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023257-B1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-06-30 | — | — | EP | disclosed |
| EP-0023257-A1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-02-04 | — | — | EP | disclosed |