Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | P4HB | P07237 | 3/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25176277 | 0.82 | PLCG1 (0.48) | PLCG1PDK1PDK2PDK3PDK4 | |
| SCHEMBL27095790 | 0.80 | ALDH1A1 (0.55) | PLCG1CNR2CNR1PDK2PDK4 | |
| SCHEMBL11218434 | 0.78 | P4HB (0.39) | CNR2TMPRSS4P4HBANO1TRPV4 | |
| SCHEMBL27095791 | 0.78 | ALDH1A1 (0.50) | CNR2CNR1TMPRSS4 | |
| SCHEMBL11703903 | 0.78 | NR1H4 (0.45) | PLCG1CNR2CNR1TMPRSS4 | |
| SCHEMBL6072565 | 0.77 | VCAM1 (0.48) | PLCG1 | |
| SCHEMBL5355618 | 0.77 | PLCG1 (0.48) | PLCG1CNR2CNR1 | |
| SCHEMBL5368308 | 0.76 | ALDH1A1 (0.57) | P4HBTRPV4 | |
| SCHEMBL29437966 | 0.76 | ALDH1A1 (0.57) | P4HBTRPV4 | |
| SCHEMBL4700026 | 0.75 | CNR2 (0.50) | PLCG1CNR2CNR1EGLN1P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |