Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214551 | 0.84 | MAPT (0.53) | ALOX15TSHRHSD17B10MAPTALDH1A1 | |
| Enciprazine SCHEMBL1649926 | 0.77 | MAPT (0.71) | ALOX15TSHRHSD17B10MAPTALDH1A1 | |
| Enciprazine SCHEMBL584730 | 0.76 | MAPT (0.74) | ALOX15TSHRHSD17B10MAPTALDH1A1 | |
| Enciprazine SCHEMBL29710915 | 0.76 | MAPT (0.74) | ALOX15TSHRHSD17B10MAPTALDH1A1 | |
| SCHEMBL10571472 | 0.76 | DRD2 (0.61) | MAPTLMNADRD2DRD3 | |
| Enciprazine SCHEMBL10569674 | 0.76 | MAPT (0.76) | ALOX15TSHRMAPTALDH1A1LMNA | |
| Enciprazine SCHEMBL668369 | 0.76 | MAPT (0.76) | ALOX15TSHRMAPTALDH1A1LMNA | |
| SCHEMBL11218869 | 0.75 | HSP90AB1 (0.50) | TSHRMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL29386890 | 0.74 | GAA (0.61) | DRD2DRD3 | |
| SCHEMBL11212821 | 0.73 | MAPT (0.62) | ALOX15TSHRHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335126-A | SEDATIVES, TRANQUILIZERS, AND ANTIPYRETICS; NEUROLEPTIC AND ANTIEDEMIC AGENTS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |