Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214551 | 0.89 | MAPT (0.53) | HSP90AB1MEN1KMT2ATSHRLMNA | |
| SCHEMBL11212942 | 0.88 | HSP90AB1 (0.61) | HSP90AB1MEN1KMT2ALMNADRD2 | |
| SCHEMBL11814329 | 0.77 | CACNA1G (0.58) | HSP90AB1LMNADRD2ALDH1A1MAPT | |
| SCHEMBL11212821 | 0.75 | MAPT (0.62) | MEN1KMT2ATSHRLMNADRD2 | |
| SCHEMBL11216643 | 0.75 | ALOX15 (0.46) | MEN1KMT2ATSHRLMNADRD2 | |
| Enciprazine SCHEMBL584730 | 0.73 | MAPT (0.74) | HSP90AB1MEN1KMT2ATSHRLMNA | |
| Enciprazine SCHEMBL29710915 | 0.73 | MAPT (0.74) | HSP90AB1MEN1KMT2ATSHRLMNA | |
| SCHEMBL11215922 | 0.73 | MAPT (0.61) | HSP90AB1MEN1KMT2ATSHRLMNA | |
| Enciprazine SCHEMBL10569674 | 0.72 | MAPT (0.76) | HSP90AB1MEN1KMT2ATSHRLMNA | |
| Enciprazine SCHEMBL668369 | 0.72 | MAPT (0.76) | HSP90AB1MEN1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335126-A | SEDATIVES, TRANQUILIZERS, AND ANTIPYRETICS; NEUROLEPTIC AND ANTIEDEMIC AGENTS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |