Enciprazine

Enciprazine

SCHEMBL584730

COc1ccccc1N1CCN(CC(O)COc2cc(OC)c(OC)c(OC)c2)CC1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.74
ALDH1A1 P00352 4/20 0.74
KCNH2 Q12809 2/20 0.69
CACNA1G O43497 1/20 0.69
LMNA P02545 7/20 0.68
MEN1 O00255 5/20 0.67
KMT2A Q03164 5/20 0.67
KDM4E B2RXH2 3/20 0.67
MAPK1 P28482 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
HIF1A Q16665 2/20 0.67
TP53 P04637 2/20 0.67
NR1I2 O75469 1/20 0.67
NR3C1 P04150 1/20 0.67
ADRB1 P08588 1/20 0.67
HTR1A P08908 1/20 0.67
ADRA2A P08913 1/20 0.67
DRD2 P14416 1/20 0.67
ADRA2B P18089 1/20 0.67
ADRA2C P18825 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Enciprazine SCHEMBL29710915 1.00 MAPT (0.74) MAPTALDH1A1KCNH2CACNA1GLMNA
Enciprazine SCHEMBL668369 0.99 MAPT (0.76) MAPTALDH1A1KCNH2CACNA1GLMNA
Enciprazine SCHEMBL10569674 0.99 MAPT (0.76) MAPTALDH1A1KCNH2CACNA1GLMNA
Enciprazine SCHEMBL1649926 0.98 MAPT (0.71) MAPTALDH1A1KCNH2CACNA1GLMNA
SCHEMBL11212821 0.91 MAPT (0.62) MAPTALDH1A1KCNH2CACNA1GLMNA
SCHEMBL11215922 0.90 MAPT (0.61) MAPTALDH1A1KCNH2CACNA1GLMNA
SCHEMBL29074454 0.89 MAPT (0.71) MAPTALDH1A1KCNH2CACNA1GLMNA
SCHEMBL17313697 0.89 KCNH2 (0.78) MAPTALDH1A1KCNH2CACNA1GLMNA
SCHEMBL7711429 0.87 MAPT (0.76) MAPTALDH1A1KCNH2CACNA1GLMNA
SCHEMBL11214311 0.86 MAPT (0.64) MAPTALDH1A1KCNH2CACNA1GLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 611 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
WO-2023212244-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS, INC. (US) 2023-11-02 WO claimed
US-20220273600-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-09-01 US claimed
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 EP claimed
US-20220146492-A1 CELL MEMBRANE PERMEABILITY RESTORING THERAPY SHINE IAN BASIL (US) 2022-05-12 US claimed
EP-3953000-A1 CELL MEMBRANE PERMEABILITY RESTORING THERAPY Shine, Ian Basil (US) 2022-02-16 EP claimed
US-20200345722-A1 ABUSE-DETERRENT DRUG FORMULATIONS COLLEGIUM PHARMACEUTICAL INC (US) 2020-11-05 US claimed
US-20200345723-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITIONS OF OPIOIDS AND OTHER DRUGS COLLEGIUM PHARMACEUTICAL INC (US) 2020-11-05 US claimed
WO-2020210643-A1 CELL MEMBRANE PERMEABILITY RESTORING THERAPY SHINE IAN BASIL (US) 2020-10-15 WO claimed
EP-3651759-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF Syneurx International (Taiwan) Corp. (TW) 2020-05-20 EP claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2007036671-A2 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL GALENIC FORM COMPRISING SAME FLAMEL TECHNOLOGIES (FR) 2007-04-05 WO claimed
EP-1765292-A1 ABUSE-DETERRENT DRUG FORMULATIONS Collegium Pharmaceutical, Inc. (US) 2007-03-28 EP claimed
WO-2005123039-A1 ABUSE-DETERRENT DRUG FORMULATIONS COLLEGIUM PHARMACEUTICAL, INC. (US) 2005-12-29 WO claimed
US-20050281748-A1 Abuse-deterrent drug formulations COLLEGIUM PHARMACEUTICAL, INC. 2005-12-22 US claimed
EP-1594467-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITIONS OF OPIOIDS AND OTHER DRUGS Collegium Pharmaceutical, Inc. (US) 2005-11-16 EP claimed
US-20040052731-A1 Abuse-deterrent pharmaceutical compositions of opiods and other drugs COLLEGIUM PHARMACEUTICALS, INC. 2004-03-18 US claimed
WO-2004004693-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITIONS OF OPIODS AND OTHER DRUGS COLLGEGIUM PHARMACEUTICAL (US) 2004-01-15 WO claimed
EP-0229947-B1 NOVEL CRYSTALLINE SALTS OF ARYLOXY-PROPANOLAMINES, THEIR PREPARATION AND THEIR USE RORER INTERNATIONAL (OVERSEAS) INC. (US) 1991-03-13 EP claimed
EP-0229947-A1 Novel crystalline salts of aryloxy-propanolamines, their preparation and their use RORER INTERNATIONAL (OVERSEAS) INC. (US) 1987-07-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273600-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF SLC1A2, SLC6A5, SLC1A1 MAPT 2140/4885ALDH1A1 2738/4885KCNH2 491/4885
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS HTR2A, HTR5A, HTR6 MAPT 1647/4885ALDH1A1 913/4885KCNH2 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.