SCHEMBL27959986

SCHEMBL27959986

CCC(=O)Cc1cc(C)ccc1C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.46
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TSHR P16473 2/20 0.41
SLC22A12 Q96S37 1/20 0.40
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SRC P12931 1/20 0.39
KDM4E B2RXH2 2/20 0.38
HTT P42858 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GAA P10253 1/20 0.38
MAPK8 P45983 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13091046 0.85 NPC1 (0.43) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL3015869 0.83 HTT (0.45) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL13068104 0.83 AMY1A (0.50) MEN1KMT2AHTTMAPTNPSR1
SCHEMBL9969945 0.80 TAAR1 (0.48) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL29375293 0.80 SRC (0.58) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL1259688 0.80 TAAR1 (0.48) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL37138 0.80 SRC (0.58) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL11009522 0.80 L3MBTL1 (0.44) TAAR1KMT2ATSHRSMN1; SMN2KDM4E
SCHEMBL14077960 0.79 NLRP3 (0.43) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL25709157 0.79 TAAR1 (0.41) TAAR1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103725370-A Pure petroleum base based energy-saving anti-friction novel lubricating oil and preparation method YAO FANGFEI 2014-04-16 CN disclosed