SCHEMBL37138

SCHEMBL37138

Cc1ccc(C)c(CC(=O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.58
MAPT P10636 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALOX15 P16050 2/20 0.53
SLC22A12 Q96S37 1/20 0.51
PTGS2 P35354 5/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
TAAR1 Q96RJ0 1/20 0.48
TSHR P16473 2/20 0.47
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
ABCB11 O95342 1/20 0.44
PTGS1 P23219 1/20 0.44
PPARG P37231 1/20 0.44
NR1I3 Q14994 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375293 1.00 SRC (0.58) SRCMAPTSMN1; SMN2ALOX15SLC22A12
SCHEMBL28007584 0.98 SRC (0.56) SRCMAPTSMN1; SMN2ALOX15SLC22A12
Hydrochloric Acid SCHEMBL2531969 0.98 SRC (0.56) SRCMAPTSMN1; SMN2ALOX15SLC22A12
SCHEMBL12258207 0.85 SRC (0.65) SRCMAPTSMN1; SMN2ALOX15SLC22A12
SCHEMBL19512763 0.85 RXRA (0.49) SRCMAPTSMN1; SMN2ALOX15SLC22A12
SCHEMBL9969945 0.83 TAAR1 (0.48) SRCSLC22A12MEN1KMT2ANPC1
SCHEMBL1257788 0.83 SRC (0.62) SRCMAPTSMN1; SMN2ALOX15PTGS2
SCHEMBL1259688 0.83 TAAR1 (0.48) SRCSLC22A12MEN1KMT2ANPC1
SCHEMBL15780476 0.83 SRC (0.62) SRCMAPTSMN1; SMN2ALOX15SLC22A12
SCHEMBL37438 0.82 TAAR1 (0.47) SRCSMN1; SMN2SLC22A12PTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886737-A Spiroteine framework compound and preparation method and application thereof 安徽农业大学 2024-04-16 CN claimed
CN-115872849-A Method for preparing 2, 5-dimethylphenylacetic acid 阜新睿光氟化学有限公司 2023-03-31 CN claimed
CN-114790136-A Preparation method and application of active trivalent organic chromium compound 中国石油天然气股份有限公司 2022-07-26 CN claimed
CN-110305010-B Preparation method of 2, 5-dimethylphenylacetic acid 江苏中旗科技股份有限公司 2022-05-13 CN claimed
CN-113603968-A Toughening modified PP plastic particle 安徽成龙塑业科技有限公司 2021-11-05 CN claimed
CN-111072470-A Method for preparing 2, 5-dimethyl phenylacetyl chloride 大连奇凯医药科技有限公司 2020-04-28 CN claimed
CN-107250102-B Method for producing benzidine from azobenzene by ruthenium catalysis 拜耳作物科学股份公司 2020-04-24 CN claimed
CN-110357774-A A method of 2,5- dimethyl phenyl acetic acid is prepared by raw material of 2,5- dimethyl halobenzene 江苏中旗科技股份有限公司 2019-10-22 CN claimed
CN-110305009-A A method of 2,5- dimethyl phenyl acetic acid is synthesized by 2,5- dimethylbenzyl halogen 江苏中旗科技股份有限公司 2019-10-08 CN claimed
CN-110305010-A Preparation method of 2, 5-dimethylphenylacetic acid 江苏中旗科技股份有限公司 2019-10-08 CN claimed
US-8664424-B2 Method for preparing 2,5-dimethylphenylacetic acid LIANHE CHEMICAL TECHNOLOGY CO., LTD (CN) 2014-03-04 US claimed
EP-2562152-A1 A METHOD FOR PREPARING 2,5-DIMETHYLPHENYLACETIC ACID Lianhe Chemical Technology Co., Ltd. (CN) 2013-02-27 EP claimed
US-20130046108-A1 METHOD FOR PREPARING 2,5-DIMETHYLPHENYLACETIC ACID JIANGSU LIANHE CHEMICAL TECHNOLOGY CO., LTD. (CN) 2013-02-21 US claimed
JP-4668212-B2 2011-04-13 JP claimed
EP-1713755-B1 METHOD FOR PRODUCING 2,5-DIMETHYLPHENYL ACETIC ACID BAYER CROPSCIENCE AG (DE) 2010-01-13 EP claimed
US-7579500-B2 Method for producing 2,5-dimethylphenyl acetic acid ARCHER-DANIELS-MIDLAND COMPANY (US) 2009-08-25 US claimed
US-20080234501-A1 Method for Producing 2,5-Dimethylphenyl Acetic Acid BAYER CROPSCIENCE AG (DE) 2008-09-25 US claimed
JP-2007522139-A 2007-08-09 JP claimed
EP-1713755-A1 METHOD FOR PRODUCING 2,5-DIMETHYLPHENYL ACETIC ACID Bayer CropScience Aktiengesellschaft (DE) 2006-10-25 EP claimed
WO-2005075401-A1 METHOD FOR PRODUCING 2,5-DIMETHYLPHENYL ACETIC ACID BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-08-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130046108-A1 METHOD FOR PREPARING 2,5-DIMETHYLPHENYLACETIC ACID DDC, DDT, HPD SRC 2096/4885MAPT 1888/4885SMN1; SMN2 4491/4885
US-20080234501-A1 Method for Producing 2,5-Dimethylphenyl Acetic Acid DDC, HACL2, DDT SRC 3019/4885MAPT 3918/4885SMN1; SMN2 4846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.