Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210417 | 0.83 | CYP2C9 (0.42) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11212104 | 0.80 | ESR1 (0.41) | MAPTALDH1A1LMNAMEN1GAA | |
| SCHEMBL7402774 | 0.80 | ALDH1A1 (0.44) | MAPTACHEALOX5ALDH1A1LMNA | |
| SCHEMBL7823663 | 0.80 | ALDH1A1 (0.44) | MAPTACHEALOX5ALDH1A1LMNA | |
| SCHEMBL11212846 | 0.78 | HDAC3 (0.44) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL11212918 | 0.78 | CYP1A2 (0.44) | ALOX5CES2CES1SMN1; SMN2MEN1 | |
| SCHEMBL11218294 | 0.78 | BRD4 (0.44) | LMNACES2CES1MEN1KMT2A | |
| SCHEMBL11214233 | 0.78 | TRPA1 (0.38) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL11210447 | 0.78 | CES2 (0.45) | MAPTALOX5ALDH1A1CES2CES1 | |
| SCHEMBL9781797 | 0.77 | SRC (0.46) | LMNACES2CES1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |