SCHEMBL11217809

SCHEMBL11217809

O=C(O)CCC(=O)Cc1ccc(Cl)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.48
ACLY P53396 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.45
ERCC1 P07992 2/20 0.44
ERCC4 Q92889 2/20 0.44
P2RX7 Q99572 1/20 0.44
PDPK1 O15530 1/20 0.44
HPGD P15428 1/20 0.44
NR4A2 P43354 1/20 0.44
IDO1 P14902 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28940593 0.85 IDO1 (0.54) TP53ERCC1ERCC4P2RX7IDO1
SCHEMBL11311719 0.84 ALDH1A1 (0.50) ALDH1A1TP53ERCC1ERCC4P2RX7
SCHEMBL29419329 0.83 CHRM1 (0.57) ALDH1A1TP53ERCC1ERCC4P2RX7
SCHEMBL260512 0.83 CHRM1 (0.57) ALDH1A1TP53ERCC1ERCC4P2RX7
SCHEMBL9210610 0.83 SLC6A2 (0.46) ERCC1ERCC4P2RX7IDO1
Hydrochloric Acid SCHEMBL2532568 0.82 CHRM1 (0.55) ALDH1A1TP53ERCC1ERCC4P2RX7
SCHEMBL586345 0.80 PDPK1 (0.59) ACLYALDH1A1PDPK1HPGD
SCHEMBL3017863 0.80 MAPK1 (0.52) ALDH1A1ERCC1ERCC4P2RX7HPGD
SCHEMBL30567601 0.80 PDPK1 (0.59) ACLYALDH1A1PDPK1HPGD
SCHEMBL31204467 0.80 IDO1 (0.53) TP53ERCC1ERCC4P2RX7HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338122-A MITICIDES, HERBICIDES UNION CARBIDE CORPORATION (US) 1982-07-06 US disclosed
US-4283348-A SODIUM ETHOXIDE PROMOTED CYCLIZATION OF LEVULINIC ACID ESTERS UNION CARBIDE CORPORATION (US) 1981-08-11 US disclosed