SCHEMBL260512

SCHEMBL260512

O=C(O)Cc1ccc(Cl)cc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.57
KEAP1 Q14145 1/20 0.53
NFE2L2 Q16236 1/20 0.53
CYP2C9 P11712 2/20 0.53
CXCL8 P10145 1/20 0.53
IDO1 P14902 1/20 0.52
ALDH1A1 P00352 1/20 0.51
ERCC1 P07992 2/20 0.50
ERCC4 Q92889 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.50
CYP2C19 P33261 1/20 0.50
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TP53 P04637 1/20 0.50
P2RX7 Q99572 1/20 0.50
NR4A2 P43354 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419329 1.00 CHRM1 (0.57) CHRM1KEAP1NFE2L2CYP2C9CXCL8
Hydrochloric Acid SCHEMBL2532568 0.98 CHRM1 (0.55) CHRM1KEAP1NFE2L2CYP2C9CXCL8
SCHEMBL16041940 0.85 KEAP1 (0.54) CHRM1KEAP1NFE2L2CYP2C9CXCL8
SCHEMBL28940593 0.85 IDO1 (0.54) CYP2C9IDO1ERCC1ERCC4TDP1
SCHEMBL15822666 0.85 DGAT1 (0.54) CHRM1KEAP1NFE2L2CYP2C9CXCL8
SCHEMBL11311719 0.85 ALDH1A1 (0.50) IDO1ALDH1A1ERCC1ERCC4TP53
SCHEMBL11217809 0.83 PGK1 (0.48) IDO1ALDH1A1ERCC1ERCC4TP53
SCHEMBL657437 0.83 IDO1 (0.52) CYP2C9IDO1ERCC1ERCC4TDP1
SCHEMBL2578143 0.83 CXCL8 (0.57) CHRM1KEAP1NFE2L2CYP2C9CXCL8
SCHEMBL2394432 0.83 KEAP1 (0.53) CHRM1KEAP1NFE2L2CYP2C9CXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 820 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164897-A Spirotemporal compound and preparation method and application thereof 南开大学 2024-06-11 CN claimed
CN-118044539-A Application of 2, 4-dichlorophenoxyacetic acid in storage and fresh-keeping of picked fruits 华中农业大学 2024-05-17 CN claimed
CN-117886737-A Spiroteine framework compound and preparation method and application thereof 安徽农业大学 2024-04-16 CN claimed
CN-116969900-A Preparation process of 2- (2, 4-dichlorophenyl) -3- (1-H, 1,2, 4-triazolyl) propanol 安徽云帆药业有限公司 2023-10-31 CN claimed
CN-115215879-B 3-aryl-4, 5-pyranocoumarin derivative, and preparation method and application thereof 广西中医药大学 2023-10-20 CN claimed
CN-113582904-B 5-n-propyl-4-hydroxypyrrole-2-ketone derivative and preparation method and application thereof 安徽农业大学 2023-03-10 CN claimed
CN-115215879-A 3-aryl-4, 5-pyranocoumarin derivatives, and preparation method and application thereof 广西中医药大学 2022-10-21 CN claimed
CN-114478122-A Novel functional fertilizer synergist and application 郑州郑氏化工产品有限公司 2022-05-13 CN claimed
CN-215102480-U Production 2, 4-dichlorobenzene acetic acid cyanidation waste water retrieval and utilization device 酒泉亚佳化学有限公司 2021-12-10 CN claimed
CN-215102481-U Production 2, 4-dichlorobenzene acetic acid waste water retrieval and utilization device that hydrolysises 酒泉亚佳化学有限公司 2021-12-10 CN claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-1456254-A2 SUPPORTED TITANIUM-CONTAINING CATALYST FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS Polimeri Europa S.p.A. (IT) 2004-09-15 EP claimed
WO-2003054034-A2 SUPPORTED TITANIUM-CONTAINING FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS POLIMERI EUROPA S.P.A. (IT) 2003-07-03 WO claimed
EP-0710648-B1 Method for producing oxyindoles KI CHEMICAL INDUSTRY CO LTD (JP) 2002-04-03 EP claimed
US-5679799-A Method for producing oxyindoles K-I CHEMICAL INDUSTRY CO., LTD. (JP) 1997-10-21 US claimed
EP-0710648-A1 Method for producing oxyindoles K I CHEMICAL INDUSTRY CO., LTD. (JP) 1996-05-08 EP claimed
EP-0170893-B1 MICROBIOCIDAL ANIONIC SEQUESTERANTS WITH POLYVALENT METAL CATIONS FOR PERMEABILITY CORRECTION PROCESS PHILLIPS PETROLEUM COMPANY (US) 1989-08-30 EP claimed
US-4629747-A INCLUDES CROSSLINKABLE WATER SOLUBLE POLYMER PHILLIPS PETROLEUM COMPANY (US) 1986-12-16 US claimed
EP-0170893-A1 Microbiocidal anionic sequesterants with polyvalent metal cations for permeability correction process PHILLIPS PETROLEUM COMPANY (US) 1986-02-12 EP claimed
US-4552217-A Microbiocidal anionic sequesterants with polyvalent metal cations for permeability correction process PHILLIPS PETROLEUM COMPANY (US) 1985-11-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 CHRM1 3968/4885KEAP1 2845/4885NFE2L2 3435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.