Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.44 |
| ▸ | PPARA | Q07869 | 10/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356465 | 1.00 | PPARG (0.44) | PPARGPPARALDHAHSD17B10MME | |
| SCHEMBL10743703 | 0.91 | HSD17B10 (0.50) | PPARGPPARAHSD17B10PPARDMAPT | |
| SCHEMBL10847599 | 0.86 | ACACB (0.42) | PPARGPPARALDHAMMEACE | |
| SCHEMBL20594558 | 0.85 | TP53 (0.48) | PPARGPPARAHSD17B10PPARDMAPT | |
| SCHEMBL9513316 | 0.85 | TP53 (0.48) | PPARGPPARAHSD17B10PPARDMAPT | |
| SCHEMBL8687601 | 0.84 | THRB (0.57) | PPARGPPARAMMEACECPA1 | |
| SCHEMBL23520497 | 0.83 | PDCD1 (0.49) | PPARGPPARAMMEACECPA1 | |
| SCHEMBL18328861 | 0.82 | TP53 (0.49) | PPARGPPARAPPARDMAPT | |
| SCHEMBL9724830 | 0.81 | ELANE (0.57) | HSD17B10MAPTFFAR1 | |
| SCHEMBL10745842 | 0.80 | PRSS1 (0.46) | PPARGPPARAPPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035155-B1 | TRANS-4\"-ALKYLCYCLOHEXYL ESTERS OF 4'-(2-METHYLBUTYL)-4-BIPHENYLCARBOXYLIC ACID AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | Chisso Corporation (JP) | 1983-11-23 | — | — | EP | disclosed |
| EP-0035155-A1 | Trans-4\"-alkylcyclohexyl esters of 4'-(2-methylbutyl)-4-biphenylcarboxylic acid and liquid crystal compositions containing same | Chisso Corporation (JP) | 1981-09-09 | — | — | EP | disclosed |