Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 11/20 | 0.39 |
| ▸ | PPARG | P37231 | 10/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541957 | 0.85 | ACACB (0.42) | THRBACACBPPARAPPARGPPARD | |
| SCHEMBL12567796 | 0.85 | THRB (0.42) | THRBACACBPPARAPPARGPPARD | |
| SCHEMBL11665188 | 0.84 | ALDH1A1 (0.42) | THRBACACBPPARAPPARGPPARD | |
| SCHEMBL9356465 | 0.84 | PPARG (0.44) | PPARAPPARGPPARDMMEACE | |
| SCHEMBL11218143 | 0.84 | PPARG (0.44) | PPARAPPARGPPARDMMEACE | |
| SCHEMBL10743703 | 0.84 | HSD17B10 (0.50) | ACACBPPARAPPARGPPARD | |
| SCHEMBL10308954 | 0.83 | THRB (0.41) | THRBACACBPPARAPPARGPPARD | |
| SCHEMBL10409028 | 0.82 | THRB (0.45) | THRBACACBPPARAPPARGPPARD | |
| SCHEMBL10408342 | 0.82 | THRB (0.45) | THRBACACBPPARAPPARGPPARD | |
| SCHEMBL10847599 | 0.82 | ACACB (0.42) | ACACBPPARAPPARGPPARDMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750051-A | COPOLYMERIZABLE MATERIAL FOR POLYMERIC FILM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-12 | — | — | US | disclosed |