Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216050 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL11218672 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL8174576 | 0.83 | PKM (0.47) | ALDH1A1GAATDP1KCNQ3KCNQ2 | |
| SCHEMBL11218202 | 0.83 | TDP1 (0.37) | SMN1; SMN2ALDH1A1LMNATDP1KCNQ3 | |
| SCHEMBL11211576 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1LMNAGAAL3MBTL1 | |
| SCHEMBL22504134 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1LMNAGAARAB9A | |
| SCHEMBL1395735 | 0.74 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1LMNAGAARAB9A | |
| SCHEMBL11212870 | 0.74 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1LMNATDP1NPC1 | |
| SCHEMBL11212191 | 0.72 | EPHX1 (0.49) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11208287 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1LMNAGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |