Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216037 | 0.87 | FABP4 (0.41) | TDP1RAB9AKMT2ASMN1; SMN2LMNA | |
| SCHEMBL11218670 | 0.84 | DAO (0.43) | TDP1ANPEPRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11218207 | 0.83 | SMN1; SMN2 (0.50) | TDP1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL8174576 | 0.83 | PKM (0.47) | TDP1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL11211574 | 0.77 | ALDH1A1 (0.41) | KMT2ALMNAMAPTPPARDPOLB | |
| SCHEMBL11212864 | 0.74 | ALDH1A1 (0.50) | TDP1RAB9AKMT2ASMN1; SMN2LMNA | |
| SCHEMBL11218295 | 0.74 | KMT2A (0.54) | RAB9AKMT2ASMN1; SMN2LMNAPOLB | |
| SCHEMBL11212188 | 0.72 | APEX1 (0.45) | KMT2ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL11208284 | 0.72 | POLB (0.43) | TDP1ANPEPCA1CA2CA7 | |
| SCHEMBL11524991 | 0.71 | FABP4 (0.52) | RAB9APPARDALDH1A1FABP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |