SCHEMBL1121857

SCHEMBL1121857

CCCCCCCC(=O)Oc1cccc2cccnc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
GAA P10253 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
METAP2 P50579 1/20 0.52
METAP1 P53582 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
POLM Q9NP87 2/20 0.52
POLK Q9UBT6 2/20 0.52
POLL Q9UGP5 2/20 0.52
POLH Q9Y253 2/20 0.52
KDM4E B2RXH2 4/20 0.50
POLB P06746 1/20 0.50
KMT2A Q03164 6/20 0.49
HSP90AA1 P07900 1/20 0.49
USP2 O75604 1/20 0.48
MEN1 O00255 5/20 0.47
NPSR1 Q6W5P4 3/20 0.47
ALOX15 P16050 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10752030 1.00 LMNA (0.55) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL8822078 1.00 LMNA (0.55) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL10828205 0.92 POLM (0.56) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL27574702 0.90 POLM (0.54) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL10751742 0.89 LMNA (0.60) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL8352456 0.87 MEN1 (0.46) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL4457246 0.86 LMNA (0.66) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL10750474 0.83 LMNA (0.63) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL13396849 0.83 LMNA (0.57) LMNAL3MBTL1GAASMN1; SMN2METAP2
SCHEMBL28063137 0.83 LMNA (0.48) LMNAL3MBTL1GAASMN1; SMN2METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed