Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752030 | 0.83 | LMNA (0.55) | LMNAL3MBTL1GAASMN1; SMN2METAP2 | |
| SCHEMBL8822078 | 0.83 | LMNA (0.55) | LMNAL3MBTL1GAASMN1; SMN2METAP2 | |
| SCHEMBL1121857 | 0.83 | LMNA (0.55) | LMNAL3MBTL1GAASMN1; SMN2METAP2 | |
| SCHEMBL28621538 | 0.82 | LMNA (0.49) | LMNAL3MBTL1GAASMN1; SMN2METAP2 | |
| SCHEMBL15548255 | 0.80 | PRSS1 (0.51) | LMNAL3MBTL1HDAC6KDM4EMEN1 | |
| SCHEMBL15547726 | 0.80 | PRSS1 (0.51) | LMNAL3MBTL1HDAC6KDM4EMEN1 | |
| SCHEMBL15548923 | 0.80 | PRSS1 (0.51) | LMNAL3MBTL1HDAC6KDM4EMEN1 | |
| SCHEMBL10752189 | 0.79 | LMNA (0.60) | LMNAL3MBTL1GAASMN1; SMN2METAP2 | |
| SCHEMBL15548954 | 0.79 | PRSS1 (0.49) | LMNAHDAC6KDM4EMEN1KMT2A | |
| SCHEMBL28207518 | 0.79 | L3MBTL1 (0.50) | L3MBTL1GAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501264-A | The preparation method of diazabicyclooctane derivative | 明治制果药业株式会社 | 2017-12-22 | — | — | CN | disclosed |
| CN-105555787-B | Process for preparation of diazabicyclooctane derivatives and intermediates therefor | 明治制果药业株式会社 | 2017-08-08 | — | — | CN | disclosed |
| CN-105555787-A | Process for preparation of diazabicyclooctane derivatives and intermediates therefor | MEIJI SEIKA PHARMA CO LT | 2016-05-04 | — | — | CN | disclosed |