Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | METAP2 | P50579 | 1/20 | 0.63 |
| ▸ | METAP1 | P53582 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751742 | 0.91 | LMNA (0.60) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL6983292 | 0.87 | LMNA (0.63) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL10750474 | 0.87 | LMNA (0.63) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL8822078 | 0.86 | LMNA (0.55) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL1121857 | 0.86 | LMNA (0.55) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL10752030 | 0.86 | LMNA (0.55) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL13396849 | 0.85 | LMNA (0.57) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL10751830 | 0.84 | LMNA (0.60) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL28459061 | 0.84 | LMNA (0.69) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 | |
| SCHEMBL22722222 | 0.83 | LMNA (0.50) | LMNAL3MBTL1SMN1; SMN2GAAMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |