SCHEMBL1121871

SCHEMBL1121871

CCCCCCCC(=O)Oc1cc2ccc(F)cc2[nH]1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.40
DAO P14920 1/20 0.40
DDO Q99489 1/20 0.40
GSK3B P49841 1/20 0.40
FLT3 P36888 2/20 0.40
POLM Q9NP87 1/20 0.40
POLK Q9UBT6 1/20 0.40
POLL Q9UGP5 1/20 0.40
POLH Q9Y253 1/20 0.40
ALOX15 P16050 1/20 0.40
GHSR Q92847 1/20 0.39
HTR1A P08908 1/20 0.39
HTR1B P28222 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TOP2A P11388 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122030 0.85 ALOX15 (0.53) DAOGSK3BFLT3ALOX15
SCHEMBL1122185 0.83 PDGFRB (0.51) POLMPOLKPOLLPOLHALOX15
SCHEMBL29933814 0.81 PDGFRB (0.52) FLT3ALOX15KMT2ASMN1; SMN2KDM4E
SCHEMBL3414920 0.79 DAO (0.50) DAODDOFLT3KDM4E
SCHEMBL1122179 0.77 HTR1A (0.41) POLMPOLKPOLLPOLHALOX15
SCHEMBL1121978 0.77 HDAC3 (0.45) GSK3BFLT3POLMPOLKPOLL
SCHEMBL15558761 0.75 ALOX15 (0.62) POLMPOLKPOLLPOLHALOX15
SCHEMBL15558002 0.75 ALOX15 (0.62) POLMPOLKPOLLPOLHALOX15
SCHEMBL1121835 0.75 CYP1A2 (0.38) NAAAGSK3BALOX15HTR1AHTR1B
SCHEMBL1121872 0.75 HTR2A (0.48) GSK3BPOLMPOLKPOLLPOLH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed