Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | DDO | Q99489 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 5/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414863 | 0.87 | KDM4E (0.58) | DAOFLT3KDM4EPDPK1ALDH1A1 | |
| SCHEMBL3411403 | 0.80 | DAO (0.50) | DAODDOFLT3KDM4EALDH1A1 | |
| SCHEMBL3381701 | 0.80 | HRH4 (0.43) | KDM4EAHR | |
| SCHEMBL3418189 | 0.80 | ALOX15 (0.52) | DAOFLT3KDM4ELMNAHPGD | |
| SCHEMBL1822936 | 0.79 | EIF4A3 (0.40) | DAOKDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL1121871 | 0.79 | NAAA (0.40) | DAODDOFLT3KDM4E | |
| SCHEMBL3420585 | 0.78 | FLT3 (0.54) | FLT3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1833251 | 0.77 | KDM4E (0.55) | DAODDOFLT3KDM4EALDH1A1 | |
| SCHEMBL3003568 | 0.75 | FLT3 (0.49) | DAODDOFLT3KDM4EALDH1A1 | |
| SCHEMBL9234544 | 0.74 | ALDH1A1 (0.39) | KDM4EPDPK1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |