Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.58 |
| ▸ | CETP | P11597 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346162 | 0.87 | CETP (0.54) | ALDH1A1KMT2ABLMMEN1LMNA | |
| SCHEMBL14355937 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KMT2ABLMMEN1LMNA | |
| SCHEMBL11222976 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2ABLMMEN1LMNA | |
| SCHEMBL28693497 | 0.80 | CETP (0.48) | ALDH1A1KMT2ABLMMEN1LMNA | |
| SCHEMBL4011016 | 0.78 | ALDH1A1 (0.65) | ALDH1A1KMT2ABLMMEN1LMNA | |
| SCHEMBL11848833 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KMT2ABLMMEN1LMNA | |
| SCHEMBL28277559 | 0.77 | MAPT (0.62) | ALDH1A1KMT2AMEN1LMNANPSR1 | |
| SCHEMBL14444902 | 0.76 | CETP (0.43) | ALDH1A1KMT2AMEN1LMNANPSR1 | |
| SCHEMBL28124394 | 0.76 | HDAC3 (0.61) | ALDH1A1KMT2ABLMMEN1LMNA | |
| SCHEMBL2188873 | 0.74 | HPGD (0.66) | ALDH1A1KMT2AMEN1LMNAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250525-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-07-31 | — | — | US | disclosed |
| US-4356022-A | INSECTICIDES; MITICIDES; FUNGICIDES | STAUFFER CHEMICAL COMPANY (US) | 1982-10-26 | — | — | US | disclosed |
| US-4283395-A | S-Alkyl and alkenyl-thiophenylacetamido thiophosphates and phosphonates and method of controlling insects | STAUFFER CHEMICAL COMPANY (US) | 1981-08-11 | — | — | US | disclosed |