Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218848 | 0.87 | ALDH1A1 (0.63) | CETPALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13212281 | 0.86 | CETP (0.71) | CETPITGB3ITGAVALDH1A1NPC1 | |
| SCHEMBL26804182 | 0.83 | CETP (0.51) | CETPITGB3ITGAVALDH1A1NPC1 | |
| SCHEMBL28693497 | 0.83 | CETP (0.48) | CETPALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8619629 | 0.81 | MAPK1 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28277559 | 0.80 | MAPT (0.62) | ALOX15ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14444902 | 0.79 | CETP (0.43) | CETPALOX15ALDH1A1NPC1RAB9A | |
| SCHEMBL5542638 | 0.78 | ALDH1A1 (0.53) | CETPALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17444748 | 0.76 | PARP14 (0.63) | ALOX15ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14355939 | 0.75 | MAPT (0.44) | CETPALOX15ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698373-A | Preparation method of N- (2- (methylthio) phenyl) acetamide compound and purification method thereof | 温州大学 | 2020-01-17 | — | — | CN | disclosed |