Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.35 |
| ▸ | RXRB | P28702 | 11/20 | 0.35 |
| ▸ | RARB | P10826 | 9/20 | 0.35 |
| ▸ | RARG | P13631 | 8/20 | 0.35 |
| ▸ | RXRG | P48443 | 7/20 | 0.35 |
| ▸ | RARA | P10276 | 6/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047286 | 0.86 | RXRA (0.46) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL3179509 | 0.74 | CYP3A4 (0.37) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL24618514 | 0.73 | AKR1B1 (0.36) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL2224319 | 0.73 | KDM1A (0.35) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL9446453 | 0.73 | KDM4E (0.38) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL9721391 | 0.73 | OPRM1 (0.41) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL10533866 | 0.71 | CA1 (0.42) | RXRARXRBRXRGCYP3A4 | |
| SCHEMBL22180771 | 0.71 | RARB (0.41) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL2353102 | 0.69 | HTR2A (0.39) | — | |
| SCHEMBL3552820 | 0.68 | RXRA (0.41) | RXRARXRBRARBRARGRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002742-B1 | STILBENE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THESE STILBENE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-04-14 | — | — | EP | disclosed |