SCHEMBL2353102

SCHEMBL2353102

CC1(C)CC(C)(C)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.39
NOTUM Q6P988 1/20 0.38
KDM1A O60341 1/20 0.38
PDK2 Q15119 1/20 0.36
PDK4 Q16654 1/20 0.36
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30695310 1.00 HTR2A (0.39) HTR2ANOTUMKDM1APDK2PDK4
SCHEMBL5694129 0.86 HTR2A (0.35) HTR2ANOTUMKDM1APDK2PDK4
SCHEMBL29548964 0.86 HTR2A (0.35) HTR2ANOTUMKDM1APDK2PDK4
SCHEMBL10819306 0.84 HTR2A (0.34) HTR2ANOTUMKDM1APDK2PDK4
SCHEMBL28357421 0.82 HTR2A (0.33) HTR2ANOTUMKDM1APDK2PDK4
SCHEMBL501768 0.81 RXRA (0.42) HTR2ANOTUMKDM1A
SCHEMBL29608943 0.81 RXRA (0.42) HTR2ANOTUMKDM1A
Benzene SCHEMBL1140991 0.79 RXRA (0.44)
SCHEMBL11522414 0.78 HTR2A (0.35) HTR2ANOTUMKDM1A
SCHEMBL7789722 0.78 HTR2A (0.35) HTR2ANOTUMKDM1AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0842928-B1 PROCESS FOR PRODUCING ISOCHROMAN COMPOUNDS KAO CORP (JP) 2001-10-24 EP claimed
US-5912362-A Process for preparing isochroman compounds KAO CORPORATION (JP) 1999-06-15 US claimed
EP-0842928-A1 PROCESS FOR PRODUCING ISOCHROMAN COMPOUNDS Kao Corporation (JP) 1998-05-20 EP claimed
US-4541948-A Perfumes containing polyalkyl substituted indan-1-ones and process for preparing the compounds P. Robertet & Cie [Societe Anomyme] (FR) 1985-09-17 US claimed
EP-0089302-B1 SUBSTITUTED POLYALKYLATED DERIVATIVES OF 1-INDANONES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PERFUMES P. ROBERTET & Cie Société Anonyme dite (FR) 1985-09-11 EP claimed
JP-8301863-A None JP disclosed
US-20260150572-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-28 US disclosed
US-20240260448-A1 Metal Complexes UDC IRELAND LIMITED (IE) 2024-08-01 US disclosed
WO-2024143273-A1 RESIN FILM, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE 株式会社レゾナック 2024-07-04 WO disclosed
US-11917901-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-06 US disclosed
WO-2022270546-A1 NEGATIVE-TYPE PHOTOSENSITIVE POLYMER, POLYMER SOLUTION, NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, AND SEMICONDUCTOR DEVICE 住友ベークライト株式会社 2022-12-29 WO disclosed
US-4980509-A Aromatic polycyclic derivatives, their process of preparation and their use in human and veterinary medicine and in cosmetics SOCIETE ANONYME DITE: L'OREAL (FR) 1990-12-25 US disclosed
US-4898864-A Bicyclic aromatic compounds, a process for their preparation and their use in cosmetics and human and veterinary medicine L'OREAL (FR) 1990-02-06 US disclosed
US-4826969-A SKIN AND EYE DISORDERS CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) 1989-05-02 US disclosed
US-4541948-A Perfumes containing polyalkyl substituted indan-1-ones and process for preparing the compounds P. Robertet & Cie [Societe Anomyme] (FR) 1985-09-17 US disclosed
US-4326055-A ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES HOFFMANN-LA ROCHE INC. (US) 1982-04-20 US disclosed
EP-0002742-B1 STILBENE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THESE STILBENE DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-04-14 EP disclosed
US-4193931-A 7-(INDANYL OR NAPHTHYL)-3-METHYL-OCTA-2,4,6-TRIENE DERIVATIVES, ANTITUMOR HOFFMANN-LA ROCHE INC. (US) 1980-03-18 US disclosed
EP-0002742-A1 Stilbene derivatives, their preparation and medicines containing these stilbene derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OTC, OCIAD1 HTR2A 2863/4885NOTUM 230/4885KDM1A 2146/4885
US-20260150572-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OPRD1, CHRND HTR2A 4271/4885NOTUM 4355/4885KDM1A 3428/4885
US-11917901-B2 Metal complexes MCOLN2, MCOLN1, AP1M1 HTR2A 4427/4885NOTUM 4042/4885KDM1A 3005/4885
US-20240260448-A1 Metal Complexes SOD1, AP1M1, AP3M1 HTR2A 4632/4885NOTUM 3335/4885KDM1A 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.