Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27667565 | 0.95 | LMNA (0.44) | KMT2ALMNAMEN1ALDH1A1KDM4E | |
| SCHEMBL137120 | 0.93 | F2 (0.50) | KMT2ALMNAMEN1ALDH1A1F2 | |
| SCHEMBL81874 | 0.89 | HTR6 (0.44) | KMT2ALMNAMEN1ALDH1A1KDM4E | |
| SCHEMBL15159826 | 0.87 | F2 (0.46) | KMT2ALMNAMEN1ALDH1A1F2 | |
| Hydrogen Sulfide SCHEMBL28252271 | 0.87 | HTR6 (0.42) | KMT2ALMNAMEN1ALDH1A1KDM4E | |
| Phosphine SCHEMBL28308716 | 0.87 | HTR6 (0.42) | KMT2ALMNAMEN1ALDH1A1KDM4E | |
| Methane SCHEMBL29217844 | 0.87 | HTR6 (0.42) | KMT2ALMNAMEN1ALDH1A1KDM4E | |
| Acetonitrile SCHEMBL10504217 | 0.84 | GLA (0.44) | KMT2ALMNAMEN1ALDH1A1MAPT | |
| SCHEMBL10823807 | 0.82 | CA1 (0.43) | LMNAALDH1A1MAPTF2PRSS1 | |
| SCHEMBL2724222 | 0.81 | CA12 (0.48) | ALDH1A1GAACA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090366-A1 | 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-05 | — | — | EP | disclosed |