SCHEMBL81874

SCHEMBL81874

[N-]=[N+]=NS(=O)(=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.44
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
PLA2G7 Q13093 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA14 Q9ULX7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28308716 0.98 HTR6 (0.42) HTR6KMT2AALDH1A1KDM4EMAPT
Hydrogen Sulfide SCHEMBL28252271 0.98 HTR6 (0.42) HTR6KMT2AALDH1A1KDM4EMAPT
Methane SCHEMBL29217844 0.98 HTR6 (0.42) HTR6KMT2AALDH1A1KDM4EMAPT
Toluene SCHEMBL27667565 0.90 LMNA (0.44) KMT2AALDH1A1KDM4EMAPTLMNA
SCHEMBL11436284 0.89 TTR (0.41) HTR6KMT2AALDH1A1KDM4EMAPT
SCHEMBL27289399 0.89 KMT2A (0.37) HTR6KMT2AALDH1A1KDM4EMAPT
SCHEMBL10886227 0.89 TTR (0.41) HTR6KMT2AALDH1A1KDM4EMAPT
SCHEMBL11219005 0.89 KMT2A (0.50) KMT2AALDH1A1KDM4EMAPTLMNA
SCHEMBL10823807 0.88 CA1 (0.43) ALDH1A1MAPTLMNACA1CA2
SCHEMBL2724222 0.88 CA12 (0.48) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1090 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459193-B2 Method and kit for non-destructive in situ repair (relining) of deteriorated pipelines APPLIED RESIN S L (ES) 2025-11-04 US claimed
US-12460123-B2 Sulfonyl azide composition for sulfur scavenging in oilfield operations CAMERON INTERNATIONAL CORPORATION (US) 2025-11-04 US claimed
US-20250326759-A1 PROCESS FOR PREPARING 1-[5-TERT-BUTYL-3-[(1-METHYLTETRAZOL-5-YL)METHYL]TRIAZOLO[4,5-D]PYRIMIDIN-7-YL]PYRROLIDIN-3-OL HOFFMANN-LA ROCHE INC. (US) 2025-10-23 US claimed
US-20250263596-A1 SULFONYL AZIDE COMPOSITION FOR SULFUR SCAVENGING IN OILFIELD OPERATIONS CAMERON INTERNATIONAL CORPORATION 2025-08-21 US claimed
EP-4590784-A1 SULFONYL AZIDE COMPOSITION FOR SULFUR SCAVENGING IN OILFIELD OPERATIONS Cameron Technologies Limited (NL) 2025-07-30 EP claimed
CN-119943896-A Composite positive electrode material and preparation method and application thereof 深圳市德方纳米科技股份有限公司 2025-05-06 CN claimed
EP-4536663-A1 A PROCESS FOR PREPARING 1-[5-TERT-BUTYL-3-[(1-METHYLTETRAZOL-5 -YL)METHYL]TRIAZOLO[4,5-D]PYRIMIDIN-7-YL]PYRROLIDIN-3-OL F. Hoffmann-La Roche AG (CH) 2025-04-16 EP claimed
EP-4225557-B1 METHOD AND KIT FOR NON-DESTRUCTIVE IN SITU REPAIR (RELINING) OF DETERIORATED PIPELINES APPLIED RESIN S L (ES) 2025-02-19 EP claimed
CN-119463589-A Ultralow-thermal-conductivity self-rebound heat-insulation protective coating and protective coating 江苏苏博特新材料股份有限公司 2025-02-18 CN claimed
CN-119325477-A Process for the preparation of 1- [ 5-tert-butyl-3- [ (1-methyltetrazol-5-yl) methyl ] triazolo [4,5-d ] pyrimidin-7-yl ] pyrrolidin-3-ol 豪夫迈·罗氏有限公司 2025-01-17 CN claimed
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue BRITISH COLUMBIA, UNIVERSITY OF, THE (CA) 2003-01-16 US claimed
US-6506908-B2 From bicyclo(3.1.0)hexabe; decyclization; decarboxylation MERCK & CO., INC. 2003-01-14 US claimed
WO-2002076453-A1 METHODS AND COMPOSITIONS FOR PHOTO-CROSS LINKING PHOTOACTIVE COMPOUNDS TO TARGET TISSUE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-10-03 WO claimed
US-20020016492-A1 Process for preparing 3-hydroxymethyl-4-(aryl or heterocyclic)-cyclopentanones MERCK SHARP & DOHME CORP. 2002-02-07 US claimed
US-5795701-A Making of microlithographic structures with an underlayer film containing a thermolyzed azide compound INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-08-18 US claimed
US-5783361-A Microlithographic structure with an underlayer film containing a thermolyzed azide compound INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-07-21 US claimed
EP-0501294-B1 Radiation-sensitive polymers with 2-diazo-1,3-dicarbonyl groups, process for its production and its use in a positive-working recording material HOECHST AG (DE) 1994-10-26 EP claimed
US-5326826-A Binder HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-05 US claimed
EP-0501294-A1 Radiation-sensitive polymers with 2-diazo-1,3-dicarbonyl groups, process for its production and its use in a positive-working recording material HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-02 EP claimed
US-4640885-A BECOMES SOLVENT INSOLUBLE WHEN EXPOSED TO ULTRAVIOLET LIGHT ARMSTRONG WORLD INDUSTRIES, INC. (US) 1987-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326759-A1 PROCESS FOR PREPARING 1-[5-TERT-BUTYL-3-[(1-METHYLTETRAZOL-5-YL)METHYL]TRIAZOLO[4,5-D]PYRIMIDIN-7-YL]PYRROLIDIN-3-OL THPO, TPMT, TPP1 HTR6 2051/4885KMT2A 2498/4885ALDH1A1 798/4885
US-20020016492-A1 Process for preparing 3-hydroxymethyl-4-(aryl or heterocyclic)-cyclopentanones CCR1, CCR5, CCR6 HTR6 855/4885KMT2A 3504/4885ALDH1A1 2952/4885
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue LCP1, PPOX, TYR HTR6 2570/4885KMT2A 3404/4885ALDH1A1 542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.