SCHEMBL1121920

SCHEMBL1121920

CCCCCCCC(=O)Oc1cc2c(Cl)cc(Cl)c(Cl)c2[nH]1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.38
HPGD P15428 1/20 0.38
POLM Q9NP87 1/20 0.38
POLK Q9UBT6 1/20 0.38
POLL Q9UGP5 1/20 0.38
POLH Q9Y253 1/20 0.38
ALOX15 P16050 4/20 0.37
HTR1A P08908 1/20 0.36
HTR1B P28222 1/20 0.36
DGKA P23743 1/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TOP2A P11388 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122103 0.81 POLM (0.39) EPHX2HPGDPOLMPOLKPOLL
SCHEMBL1121982 0.80 ALOX15 (0.45) HPGDPOLMPOLKPOLLPOLH
SCHEMBL1121921 0.78 POLM (0.41) HPGDPOLMPOLKPOLLPOLH
SCHEMBL1122023 0.74 HTR1A (0.41) HPGDPOLMPOLKPOLLPOLH
SCHEMBL10044040 0.72 TRPV1 (0.45) HPGDALOX15DGKAKMT2ASMN1; SMN2
SCHEMBL11168309 0.72 ALOX15 (0.50) POLMPOLKPOLLPOLHALOX15
SCHEMBL5318813 0.72 ALOX15 (0.50) POLMPOLKPOLLPOLHALOX15
SCHEMBL7335421 0.72 ALOX15 (0.50) POLMPOLKPOLLPOLHALOX15
SCHEMBL1121897 0.70 CSNK2A2 (0.45) HPGDPOLMPOLKPOLLPOLH
SCHEMBL1121835 0.70 CYP1A2 (0.38) HPGDALOX15HTR1AHTR1BDGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed