SCHEMBL1121982

SCHEMBL1121982

CCCCCCCC(=O)Oc1cc2c(Cl)cc(Cl)cc2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.45
GRIN1 Q05586 1/20 0.43
GSK3B P49841 3/20 0.40
HTR1A P08908 1/20 0.39
HTR1B P28222 1/20 0.39
HPGD P15428 1/20 0.38
POLM Q9NP87 1/20 0.38
POLK Q9UBT6 1/20 0.38
POLL Q9UGP5 1/20 0.38
POLH Q9Y253 1/20 0.38
DGKA P23743 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1121920 0.80 EPHX2 (0.38) ALOX15HTR1AHTR1BHPGDPOLM
SCHEMBL1122030 0.80 ALOX15 (0.53) ALOX15GSK3B
SCHEMBL9390722 0.79 GRIN1 (0.48) ALOX15GRIN1HPGD
SCHEMBL1122023 0.77 HTR1A (0.41) ALOX15GSK3BHTR1AHTR1BHPGD
SCHEMBL1121835 0.75 CYP1A2 (0.38) ALOX15GSK3BHTR1AHTR1BHPGD
SCHEMBL1121918 0.75 GPR17 (0.45) ALOX15HTR1AHTR1BPOLMPOLK
SCHEMBL6274427 0.74 ALOX15 (0.53) ALOX15GSK3BHTR1AHTR1B
SCHEMBL1122185 0.72 PDGFRB (0.51) ALOX15POLMPOLKPOLLPOLH
SCHEMBL11878106 0.71 KMT2A (0.47) ALOX15HTR1AHTR1BHPGDPOLM
SCHEMBL1122103 0.71 POLM (0.39) ALOX15HTR1AHTR1BHPGDPOLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed