SCHEMBL112197

SCHEMBL112197

NCc1ccc(-n2cccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.61
ELOC Q15369 1/20 0.61
ELOB Q15370 1/20 0.61
POLB P06746 3/20 0.53
NSD2 O96028 1/20 0.53
GRK2 P25098 1/20 0.53
CASP6 P55212 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
AOC2 O75106 3/20 0.52
LOXL2 Q9Y4K0 3/20 0.46
HRH3 Q9Y5N1 1/20 0.46
MAPT P10636 3/20 0.45
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TAAR1 Q96RJ0 1/20 0.44
ABAT P80404 1/20 0.42
MEN1 O00255 4/20 0.42
ALDH1A1 P00352 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109402 0.80 AOC2 (0.56) VHLELOCELOBAOC2LOXL2
Hydrochloric Acid SCHEMBL21382427 0.80 VHL (0.55) VHLELOCELOBPOLBNSD2
SCHEMBL20319186 0.80 VHL (0.67) VHLELOCELOBPOLBNSD2
SCHEMBL13461836 0.76 VHL (0.61) VHLELOCELOBPOLBNSD2
SCHEMBL16242550 0.76 VHL (0.61) VHLELOCELOBPOLBNSD2
SCHEMBL1260586 0.76 VHL (0.61) VHLELOCELOBPOLBNSD2
SCHEMBL4049582 0.76 VHL (1.00) VHLELOCELOBPOLBNSD2
SCHEMBL5603565 0.76 VHL (0.61) VHLELOCELOBPOLBNSD2
SCHEMBL4240069 0.76 VHL (0.61) VHLELOCELOBPOLBNSD2
SCHEMBL28801815 0.74 VHL (0.59) VHLELOCELOBPOLBNSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016087603-A1 PROCESS FOR PREPARING A MODIFIED NATURAL RUBBER BY MEANS OF A MODIFIER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-06-09 WO claimed
US-12391781-B2 Black particles, black coating material, coating film, and black matrix for color filters SEKISUI CHEMICAL CO., LTD. (JP) 2025-08-19 US disclosed
EP-4063426-B1 BLACK PARTICLES, BLACK COATING MATERIAL, COATING FILM, AND BLACK MATRIX FOR COLOR FILTERS SEKISUI CHEMICAL CO LTD (JP) 2025-06-18 EP disclosed
US-20240383900-A1 SUBSTITUTED PYRAZOLO [1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE Carrick Therapeutics Limited (IE) 2024-11-21 US disclosed
US-12049461-B2 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections GILEAD SCIENCES, INC. (US) 2024-07-30 US disclosed
CN-117940427-A Substituted pyrazolo [1,5-a ] pyrimidine-7-amine compounds as CDK inhibitors and therapeutic uses thereof 卡里克治疗有限公司 2024-04-26 CN disclosed
EP-4355426-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE Carrick Therapeutics Limited (IE) 2024-04-24 EP disclosed
CN-114502677-B Black particles, black paint, coating film, and black matrix for color filter 积水化学工业株式会社 2023-11-14 CN disclosed
US-20220411553-A1 BLACK PARTICLES, BLACK COATING MATERIAL, COATING FILM, AND BLACK MATRIX FOR COLOR FILTERS SEKISUI CHEMICAL CO., LTD. (JP) 2022-12-29 US disclosed
WO-2022263604-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE Carrick Therapeutics Limited (IE) 2022-12-22 WO disclosed
WO-2008009077-A2 4,6-DL- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING VIRAL INFECTIONS GILEAD SCIENCES, INC. (US) 2008-01-24 WO disclosed
WO-2008003149-A2 SUBSTITUTED PTERIDINES FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS GILEAD SCIENCES , INC. (US) 2008-01-10 WO disclosed
CN-1308414-C Pyrromethene metal complex and light emitting device composition and light emitting devices using the same TORAY INDUSTRIES (JP) 2007-04-04 CN disclosed
CN-1863777-A Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor ABBOTT LAB (US) 2006-11-15 CN disclosed
CN-1257158-C N-aryl substituted-1H-pyrrole derivative possessing cardiovascular activity UNIV CHINA PHARMA (CN) 2006-05-24 CN disclosed
CN-1690162-A Pyrromethene metal complex and light emitting device composition and light emitting devices using the same TORAY INDUSTRIES (JP) 2005-11-02 CN disclosed
CN-1612663-A Light-emitting element, light-emitting device using the light-emitting element, and electric appliance using the light-emitting device SEMICONDUCTOR ENERGY LAB (JP) 2005-05-04 CN disclosed
CN-1592522-A Electroluminescent element and light-emitting device including the same SEMICONDUCTOR ENERGY LAB (JP) 2005-03-09 CN disclosed
CN-1544418-A N-aryl substituted-1H-pyrrole derivative possessing cardiovascular activity 中国药科大学 2004-11-10 CN disclosed
CN-1390841-A Methylene pyrrole metal complex, material for luminating element containing it and luminating element TORAY INDUSTRIES (JP) 2003-01-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12049461-B2 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections NR3C1, NR3C2, NR4A1 VHL 4220/4885ELOC 1168/4885ELOB 3060/4885
US-20240383900-A1 SUBSTITUTED PYRAZOLO [1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE CDK3, CDK1, CDK2 VHL 1209/4885ELOC 2130/4885ELOB 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.