Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898918 | 0.83 | MAPT (0.62) | MAPTAPPCYP3A4ASIC3 | |
| SCHEMBL12711667 | 0.78 | APP (0.47) | MAPTAPPESR1ESR2CYP3A4 | |
| SCHEMBL4379793 | 0.76 | APP (0.48) | MAPTAPPHIF1AESR1ESR2 | |
| SCHEMBL12711693 | 0.73 | MMP3 (0.47) | MAPTAPPESR1ESR2CYP3A4 | |
| SCHEMBL12391039 | 0.68 | ASIC3 (0.50) | MAPTLMNATSHRKMT2AATM | |
| SCHEMBL7035142 | 0.67 | APP (0.48) | MAPTAPPHIF1AESR1ESR2 | |
| SCHEMBL27722306 | 0.67 | APP (0.48) | MAPTAPPHIF1AESR1ESR2 | |
| SCHEMBL14400750 | 0.67 | APP (0.74) | MAPTAPPHIF1AESR1ESR2 | |
| SCHEMBL673609 | 0.67 | APP (0.74) | MAPTAPPHIF1AESR1ESR2 | |
| SCHEMBL11337910 | 0.67 | GRM5 (0.37) | MAPTCYP3A4KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322432-A | Cyclopropanecarboxylic acid alkynyl esters, processes for producing them, and their use as pesticides | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |