Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 12/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CALML3 | P27482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223001 | 0.78 | GRM2 (0.67) | GRM2MAOAMAOB | |
| SCHEMBL1223003 | 0.78 | GRM2 (0.67) | GRM2MAOAMAOB | |
| SCHEMBL11555302 | 0.78 | GRM2 (0.51) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL11233680 | 0.78 | MAOA (0.52) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL9484103 | 0.77 | GRM2 (0.60) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL9484108 | 0.77 | GRM2 (0.60) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL9482678 | 0.76 | GRM2 (0.53) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL9482693 | 0.76 | GRM2 (0.53) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL9484141 | 0.76 | GRM2 (0.53) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL9482868 | 0.76 | GRM2 (0.50) | GRM2MAOAMAOBCALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338451-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1982-07-06 | — | — | US | disclosed |