Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | STK25 | O00506 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6371053 | 0.82 | HCAR2 (0.57) | GPR39HCAR2DAO | |
| SCHEMBL15472487 | 0.82 | MEN1 (0.47) | SMN1; SMN2NPC1RAB9AGPR39MEN1 | |
| SCHEMBL6757804 | 0.81 | ALOX15 (0.48) | KMT2AAURKARPS6KB1AURKB | |
| SCHEMBL11215462 | 0.81 | KMT2A (0.46) | SMN1; SMN2NPC1RAB9AGPR39MEN1 | |
| SCHEMBL16939218 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AGPR39MEN1 | |
| SCHEMBL14524215 | 0.78 | MAPK1 (0.61) | SMN1; SMN2NPC1RAB9AGPR39MEN1 | |
| SCHEMBL11215060 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AGPR39MEN1 | |
| SCHEMBL18407323 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AGPR39MEN1 | |
| SCHEMBL16939219 | 0.74 | MEN1 (0.41) | SMN1; SMN2NPC1RAB9AGPR39MEN1 | |
| SCHEMBL4002119 | 0.74 | KMT2A (0.50) | SMN1; SMN2NPC1RAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57106665-A | — | — | None | — | — | JP | disclosed |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2021-04-20 | — | — | US | disclosed |
| JP-S57106665-A | 3-PYRAZOLECARBOXAMIDE DERIVATIVE, ITS PREPARATION, AND HERBICIDE | SHOWA DENKO KK | 1982-07-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | AHR, ARNT, NR1H2 | SMN1; SMN2 4755/4885NPC1 872/4885RAB9A 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.