SCHEMBL6757804

SCHEMBL6757804

NC(=O)c1cc(C(F)(F)F)[nH]n1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.48
CFTR P13569 9/20 0.45
RBP4 P02753 1/20 0.42
KMT2A Q03164 1/20 0.41
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
RPS6KB1 P23443 3/20 0.39
AURKA O14965 2/20 0.39
AURKB Q96GD4 2/20 0.39
CACNA1I Q9P0X4 1/20 0.39
HPGD P15428 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2360520 0.82 HCAR2 (0.52) ALOX15RBP4TP53MAPK1HSD17B10
SCHEMBL31308506 0.81 ALOX15 (0.48) ALOX15CFTRRBP4TP53MAPK1
SCHEMBL11220340 0.81 SMN1; SMN2 (0.43) KMT2ARPS6KB1AURKAAURKB
SCHEMBL3053796 0.81 ALOX15 (0.51) ALOX15CFTRRBP4TP53MAPK1
SCHEMBL17894320 0.77 ALOX15 (0.45) ALOX15CFTRRBP4TP53MAPK1
SCHEMBL19780067 0.77 MAPK1 (0.59) ALOX15CFTRRBP4KMT2AMAPK1
SCHEMBL31465029 0.77 KMT2A (0.38) KMT2AAURKB
SCHEMBL20029123 0.74
SCHEMBL31068051 0.73 KMT2A (0.38) ALOX15KMT2AMAPK1HSD17B10
SCHEMBL30345115 0.72 ALOX15 (0.41) ALOX15CFTRRBP4MAPK1CACNA1I

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3601298-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2020-02-05 EP claimed
CN-109195965-A The inhibitor that WDR5 protein-protein combines 普罗佩纶治疗公司 2019-01-11 CN claimed
WO-2018177970-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2018-10-04 WO claimed
EP-2934146-A1 COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF SE (DE) 2015-10-28 EP claimed
WO-2014095932-A1 COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF SE (DE) 2014-06-26 WO claimed
EP-1438305-A1 ARTHROPODICIDAL ANTHRANILAMIDES E. I. du Pont de Nemours and Company (US) 2004-07-21 EP claimed
WO-2003027099-A1 ARTHROPODICIDAL ANTHRANILAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-04-03 WO claimed
US-12583851-B2 Heteroaryl-substituted pyrazine derivatives as pesticides ELANCO ANIMAL HEALTH GMBH (DE) 2026-03-24 US disclosed
CN-120202204-A Novel substituted tetrahydrones benzooxazepine 巴斯夫欧洲公司 2025-06-24 CN disclosed
CN-120202194-A Substituted as fungicides tetrahydrobenzodiazepine 巴斯夫欧洲公司 2025-06-24 CN disclosed
CN-120076714-A Pyridine compounds for combating dihydroorotate dehydrogenase inhibitor-resistant phytopathogenic fungi 巴斯夫欧洲公司 2025-05-30 CN disclosed
CN-113166063-B Pesticidal compounds 巴斯夫欧洲公司 2025-02-25 CN disclosed
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-08-01 US disclosed
WO-2017076757-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2017-05-11 WO disclosed
WO-2016162371-A1 USE OF AN INSECTICIDAL CARBOXAMIDE COMPOUND AGAINST PESTS ON CULTIVATED PLANTS BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-10-13 WO disclosed
EP-3019013-A1 COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND AND A BIOPESTICIDE BASF Agro B.V. (NL) 2016-05-18 EP disclosed
WO-2015036059-A1 FUNGICIDAL PYRIMIDINE COMPOUNDS BASF SE (DE) 2015-03-19 WO disclosed
WO-2015003908-A1 COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND AND A BIOPESTICIDE BASF SE (DE) 2015-01-15 WO disclosed
EP-2700635-A1 5-Trifluoromethylpyrazole amides having herbicidal activity BASF SE (DE) 2014-02-26 EP disclosed
CN-1279038-C Arthropodicidal anthranilamides DU PONT (US) 2006-10-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583851-B2 Heteroaryl-substituted pyrazine derivatives as pesticides CBR3, CYCS, CWC15 ALOX15 1863/4885CFTR 2060/4885RBP4 4137/4885
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR DDT, NOS1, SLC11A2 ALOX15 1616/4885CFTR 1773/4885RBP4 4077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.