Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022040 | 0.85 | KMT2A (0.55) | MAPTKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL10349015 | 0.79 | KMT2A (0.40) | MAPTKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL11308025 | 0.77 | KMT2A (0.69) | MAPTKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL237839 | 0.77 | KMT2A (0.54) | MAPTKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL24426114 | 0.77 | S1PR1 (0.58) | MAPTKMT2AMEN1ATMNPSR1 | |
| Methoxymethane SCHEMBL11125655 | 0.76 | S100B (0.50) | MAPTKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL11100846 | 0.76 | CNR2 (0.45) | MAPTKMT2AMEN1ATMNPSR1 | |
| SCHEMBL7779135 | 0.76 | ALDH1A1 (0.50) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL10020928 | 0.75 | ALDH1A1 (0.49) | MAPTKMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL19036500 | 0.74 | S100B (0.38) | MAPTKMT2AMEN1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349454-A | ENCAPSULATION OF A HYDROPHOBIC-SOLVENT SOLUTION OF A DIAMINODIARYL METHANE SULFONE DERIVATIVE | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1982-09-14 | — | — | US | disclosed |