Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.85 |
| ▸ | POLB | P06746 | 1/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MMP13 | P45452 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16144546 | 0.94 | LMNA (0.76) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL12301918 | 0.92 | LMNA (0.73) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL1107141 | 0.92 | LMNA (0.73) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL17791374 | 0.90 | LMNA (0.71) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL9489979 | 0.90 | L3MBTL1 (0.86) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL765958 | 0.90 | L3MBTL1 (0.74) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL764574 | 0.90 | MMP13 (0.81) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL12144080 | 0.89 | LMNA (0.69) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL10872851 | 0.89 | LMNA (0.69) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL14562078 | 0.89 | POLB (0.69) | LMNAPOLBL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4386053-A | IMPREGNATION OF SUBSTRATE WITH ORGANIC PEROXIDE, CHROMOGEN, BUFFER AND STABILIZER | TERUMO CORPORATION (JP) | 1983-05-31 | — | — | US | claimed |
| US-4386053-A | IMPREGNATION OF SUBSTRATE WITH ORGANIC PEROXIDE, CHROMOGEN, BUFFER AND STABILIZER | TERUMO CORPORATION (JP) | 1983-05-31 | — | — | US | disclosed |