Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28258892 | 0.79 | CA2 (0.37) | CA2CA1CA12CA14LMNA | |
| SCHEMBL1038516 | 0.71 | LMNA (0.33) | LMNAMEN1KMT2AMAPTTP53 | |
| SCHEMBL1213173 | 0.71 | CA2 (0.55) | CA2CA1CA12CA14MAPT | |
| SCHEMBL995245 | 0.71 | MEN1 (0.39) | CA2CA1CA12CA14LMNA | |
| SCHEMBL5708648 | 0.69 | LMNA (0.33) | CA2CA1CA12CA14LMNA | |
| SCHEMBL1218665 | 0.69 | CA2 (0.52) | CA2CA1CA12CA14TSHR | |
| SCHEMBL11590057 | 0.69 | MEN1 (0.32) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL11571285 | 0.65 | CA1 (0.35) | CA2CA1CA12CA14LMNA | |
| Methane SCHEMBL8657931 | 0.65 | CA1 (0.68) | CA2CA1CA12CA14TP53 | |
| SCHEMBL293336 | 0.65 | CA2 (0.68) | CA2CA1CA12CA14TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336377-A | Basic dioxazine compounds | CIBA-GEIGY CORPORATION (US) | 1982-06-22 | — | — | US | disclosed |