SCHEMBL1038516

SCHEMBL1038516

O=S(=O)(O)N(CCCl)CCCl

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.32
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
HBB P68871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11590062 0.87 LMNA (0.35) LMNATP53TSHRHTTHBB
SCHEMBL11434836 0.82 MEN1 (0.38) LMNAMEN1KMT2ATSHR
SCHEMBL514600 0.73 SMN1; SMN2 (0.40) MAPT
SCHEMBL11220799 0.71 CA2 (0.55) LMNAMEN1KMT2AMAPTTP53
SCHEMBL15522987 0.71 SMN1; SMN2 (0.30)
Methane SCHEMBL11142383 0.71 SMN1; SMN2 (0.39) MAPT
Sulfuric Acid SCHEMBL5988946 0.71 SMN1; SMN2 (0.39) MAPT
SCHEMBL995245 0.71 MEN1 (0.39) LMNAMEN1KMT2AMAPTTP53
SCHEMBL999624 0.71 CA1 (0.60) TSHR
SCHEMBL11580213 0.69 CA1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6225347-B1 FOR LOWERING BLOOD PRESSURE, INHIBITING PLATELET AGGREGATION, FOR LUTEOLYTIC EFFECT, HEALING ULCER, INHIBITING GASTRIC ACID SECRETION, AS CYTOPROTECTIVE AGENT SCHERING AKTIENGESELLSCHAFT (DE) 2001-05-01 US claimed
US-5891910-A 9-halogen-(Z) prostaglandin derivatives, process for their production and their use as pharmaceutical agents SCHERING AKTIENGESELLSCHAFT (DE) 1999-04-06 US claimed
US-9796695-B2 Process for preparing benzofuran-2-carboxamide derivatives SYMED LABS LIMITED (IN) 2017-10-24 US disclosed
US-20170267655-A1 PROCESS FOR PREPARING BENZOFURAN-2-CARBOXAMIDE DERIVATIVES SYMED LABS LIMITED (IN) 2017-09-21 US disclosed
US-9682946-B2 Process for preparing benzofuran-2-carboxamide derivatives SYMED LABS LIMITED (IN) 2017-06-20 US disclosed
EP-2269611-B1 EP2 and EP4 agonists as agents for the treatment of influenza A viral infection GEMMUS PHARMA INC (US) 2016-03-23 EP disclosed
US-20150374715-A1 EP2 AND EP4 AGONISTS AS AGENTS FOR THE TREATMENT OF INFLUENZA A VIRAL INFECTION GEMMUS PHARMA INC (US) 2015-12-31 US disclosed
US-8980944-B2 EP2 and EP4 agonists as agents for the treatment of influenza a viral infection GEMMUS PHARMA INC. (US) 2015-03-17 US disclosed
US-20120190739-A1 EP2 AND EP4 AGONISTS AS AGENTS FOR THE TREATMENT OF INFLUENZA A VIRAL INFECTION GEMMUS PHARMA INC. (US) 2012-07-26 US disclosed
US-8183286-B2 EP2 and EP4 agonists as agents for the treatment of influenza a viral infection GEMMUS PHARMA INC. (US) 2012-05-22 US disclosed
EP-2269611-A2 EP2 and EP4 agonists as agents for the treatment of influenza A viral infection Bayer Schering Pharma Aktiengesellschaft (DE) 2011-01-05 EP disclosed
US-4235930-A INDUCTION OF MENSTRUATION OR ABORTION SCHERING, A.G. (DE) 1980-11-25 US disclosed
US-4219479-A STABILIZED PROSTACYCLINS, HYPOTENSIVE AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1980-08-26 US disclosed
US-4191694-A HYPOTENSIVE, ANTISECRETORY, ANTIULCER, ANTIARRHYTHMIA AGENTS; ANTICOAGULANTS, DIURETICS SCHERING AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed
US-4178381-A C-homoestratrienes SCHERING, AKTIENGESELLSCHAFT (DE) 1979-12-11 US disclosed
US-4159343-A ABORTIFICANTS, LABOR INDUCTION, MENSTRUAL CYCLE REGULATION SCHERING AKTIENGESELLSCHAFT (DE) 1979-06-26 US disclosed
US-4105792-A OXYTOCICS, ABORTION INDUCTION SCHERING AKTIENGESELLSCHAFT (DE) 1978-08-08 US disclosed
US-4081537-A PROGESTATIONAL, OVULATION INHIBITORS, NIDATION INHIBITORS SCHERING AKTIENGESELLSCHAFT (DT) 1978-03-28 US disclosed
US-4038410-A ANTI-PROTOZOAN AGENTS SCHERING AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed
US-3951959-A VAGINOTROPIC SCHERING AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267655-A1 PROCESS FOR PREPARING BENZOFURAN-2-CARBOXAMIDE DERIVATIVES HTR3C, VIL1, HTR4 LMNA 1710/4885MEN1 4630/4885KMT2A 718/4885
US-20120190739-A1 EP2 AND EP4 AGONISTS AS AGENTS FOR THE TREATMENT OF INFLUENZA A VIRAL INFECTION PTGER4, PTGER2, PTGER1 LMNA 2281/4885MEN1 4323/4885KMT2A 777/4885
US-20150374715-A1 EP2 AND EP4 AGONISTS AS AGENTS FOR THE TREATMENT OF INFLUENZA A VIRAL INFECTION PTGER4, PTGER2, PTGER1 LMNA 2281/4885MEN1 4323/4885KMT2A 777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.