Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225981 | 0.81 | HSD17B10 (0.49) | MEN1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL9171113 | 0.77 | KMT2A (0.51) | KMT2AMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL11566502 | 0.76 | TUBB4A (0.48) | MEN1KMT2AMAPTCYP1A2ALDH1A1 | |
| SCHEMBL20436746 | 0.76 | KDM4C (0.43) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL2214853 | 0.76 | PIN1 (0.76) | PIN1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL28379872 | 0.73 | PIN1 (0.58) | PIN1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9719979 | 0.73 | NPC1 (0.54) | PIN1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL28544499 | 0.73 | RAB9A (0.47) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL11570392 | 0.73 | HSD17B10 (0.34) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL26241758 | 0.72 | PIN1 (0.57) | PIN1MEN1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000574-B1 | BENZIMIDAZOLE-2 DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS | CIBA-GEIGY AG (CH) | 1982-08-04 | — | — | EP | claimed |
| EP-0000574-A1 | Benzimidazole-2 derivatives, their preparation and their use for the preparation of medicaments | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | claimed |