SCHEMBL11221076

SCHEMBL11221076

CCOC(=O)CS(=O)(=O)CCC#N

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
NLRP3 Q96P20 7/20 0.41
GAA P10253 3/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 3/20 0.36
TRPA1 O75762 1/20 0.36
TSHR P16473 1/20 0.35
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10499223 0.79 GAA (0.46) KMT2AGAAMGAMSIMGAM2
SCHEMBL8413025 0.78 GAA (0.55) KMT2AGAAMGAMSIMGAM2
SCHEMBL11232767 0.77 GAA (0.44) KMT2AGAAMGAMSIMGAM2
SCHEMBL11220004 0.76 GAA (0.52) KMT2AGAAMGAMSIMGAM2
SCHEMBL11226349 0.76 GAA (0.43) KMT2AGAAMGAMSIMGAM2
SCHEMBL11232629 0.76 CYP1A2 (0.48) KMT2AGAAMGAMSIMGAM2
SCHEMBL10498967 0.76 FAAH (0.44) KMT2AGAAMGAMSIMGAM2
SCHEMBL11219762 0.74 GAA (0.41) KMT2AGAAMGAMSIMGAM2
SCHEMBL11228333 0.74 GAA (0.41) KMT2AGAAMGAMSIMGAM2
SCHEMBL11224831 0.73 GAA (0.40) KMT2AGAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4326066-A Triazolyl coumarin compounds, processes for their preparation and their use as whiteners and laser dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1982-04-20 US disclosed