Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221822 | 1.00 | ALDH1A1 (0.51) | ALDH1A1CTSDMAPTGAAHTT | |
| SCHEMBL9476587 | 0.90 | MEN1 (0.51) | ALDH1A1CTSDMAPTGAAHTT | |
| SCHEMBL15880700 | 0.81 | PRMT1 (0.51) | ALDH1A1CTSDMAPTGAAHTT | |
| SCHEMBL11229633 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CTSDMAPTGAAHTT | |
| SCHEMBL11229636 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CTSDMAPTGAAHTT | |
| SCHEMBL7882872 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CTSDMAPTKDM4ETDP1 | |
| SCHEMBL6832634 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CTSDMAPTKDM4ETDP1 | |
| SCHEMBL11100530 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CTSDMAPTKDM4ETSHR | |
| SCHEMBL11100526 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CTSDMAPTKDM4ETSHR | |
| SCHEMBL15876035 | 0.78 | CTSD (0.46) | ALDH1A1CTSDMAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342781-A | PREVENTING AND TREATING ALLERGIC BRONCHIAL ASTHMA, RHINITIS AND SKIN DISORDERS | PFIZER INC. (US) | 1982-08-03 | — | — | US | disclosed |